ARPA-E SCALEUP Commercialization Grant
The Advanced Research Projects Agency-Energy provides large-scale non-dilutive funding to transition disruptive energy technologies from lab prototypes to commercial pilot manufacturing. SCALEUP bridges the pilot-to-production gap for clean energy startups.
SBA 7(a) Small Business Working Capital Loan
The SBA 7(a) loan program provides government-backed guarantees for commercial bank loans to growing small businesses. Startups can utilize funds for working capital, equipment expansion, refinance, and strategic acquisitions.
California Competes Tax Credit (CalCompetes)
CalCompetes is an income tax credit available to businesses expanding in California or relocating to the state. Evaluation criteria focus on job creation, capital investment, and economic impact within California.
New York State Innovation Venture Capital Fund
NYSIVCF is a $100M state-backed venture fund investing directly in high-growth New York startups. The fund co-invests alongside private lead institutional venture investors to accelerate technology commercialization.
SSBCI Venture Capital Equity Matching Fund
The State Small Business Credit Initiative (SSBCI) provides federal equity co-investment funds administered through participating states. It matches private venture capital investments 1:1 in high-growth technology startups.
DARPA SBIR Direct-to-Phase II Defense Innovation Grant
DARPA Direct-to-Phase II allows small businesses with proven feasibility data to bypass Phase I and receive up to $2M in non-dilutive funding. Focuses on groundbreaking defense capabilities, microelectronics, autonomous systems, and quantum tech.
Texas Enterprise Fund (TEF) Deal-Closing Grant
The Texas Enterprise Fund serves as a competitive deal-closing financial incentive for commercial projects considering Texas versus out-of-state sites. Grants directly reward high-wage job creation and significant capital investment in Texas.
Federal R&D Tax Credit Startup Payroll Offset
Qualified early-stage startups can apply Section 41 research tax credits against their federal payroll tax liabilities. Under the Inflation Reduction Act, eligible startups can offset up to $500,000 annually for up to 5 taxable years.
Massachusetts Life Sciences Center Seed Fund
MLSC provides seed-stage capital and convertible grant instruments to early life science startups across Massachusetts. The initiative accelerates pre-clinical validation, medical device design, and therapeutic proof-of-concept.
NIH SBIR Phase I Biomedical & Health Technology Grant
NIH SBIR grants support early-stage commercialization of innovative biomedical, clinical, and life science technologies. Phase I focuses on establishing technical merit and proof-of-concept for groundbreaking therapeutics and medical devices.
NSF SBIR Phase I Seed Funding
The National Science Foundation provides non-dilutive Phase I grants to transform high-risk, scientific breakthroughs into commercial products. Selected startups receive funding for feasibility research without surrendering equity or IP rights.
Ben Franklin Technology Partners Pre-Seed Investment
Ben Franklin Technology Partners provides early seed funding, incubators, and business support for technology startups in Pennsylvania. It has invested in thousands of PA technology founders over 40 years.
USDA NIFA SBIR Phase I Agricultural Innovation Grant
USDA NIFA SBIR Phase I awards fund high-risk research in agricultural technology, food security, forestry, biobased products, and rural community development. Grants aim to translate lab discoveries into marketable farm tech.
NASA SBIR Phase I Aeronautics & Space Tech Grant
NASA SBIR Phase I grants fund small businesses to develop aerospace, robotic, sensor, and space exploration innovations aligned with NASA mission directorates. Successful projects transition to Phase II contracts worth up to $850,000.
NIST SBIR Phase I Advanced Manufacturing Grant
NIST SBIR grants fund technological innovations in advanced manufacturing, semiconductor metrology, cybersecurity standards, and precision measurement tools.
Florida High Tech Corridor Matching Grants
The Florida High Tech Corridor Matching Grants Research Program matches industry research investments dollar-for-dollar when Florida startups collaborate with UCF or USF university researchers.
Ohio Third Frontier Technology Validation Fund (TVSF)
The Ohio Third Frontier TVSF provides grants to accelerate the commercialization of technologies developed by Ohio research institutions and early-stage startup companies.
One North Carolina Small Business SBIR Matching Grant
The One NC Small Business Program provides state matching grants for North Carolina small businesses that receive federal SBIR or STTR Phase I awards. The match bridges funding gaps to expedite commercial proof-of-concept.
EPA SBIR Phase I Environmental Innovation Grant
EPA SBIR Phase I awards fund small tech companies to develop commercial solutions for clean water, waste reduction, green building materials, and toxic chemical monitoring.
DoD AFWERX Open Topic SBIR Phase I
AFWERX Open Topic enables early-stage technology companies to adapt commercial innovations for U.S. Air Force and Space Force defense applications. Phase I funds customer discovery to identify Air Force end-users for follow-on Phase II contracts.